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Dexmedetomidine for the reduction of emergence delirium in children undergoing tonsillectomy with propofol anesthesia: A double-blind, randomized study

Paediatric Anaesthesia May 20, 2018

Tsiotou AG, et al. - Dexmedetomidine's efficacy in reducing emergence delirium in children undergoing tonsillectomy with and without adenoidectomy using total intravenous anesthesia with propofol was determined. Researchers examined the presence or absence of emergence delirium with and without dexmedetomidine as well as emergence delirium severity, time to extubation, cardiovascular stability, and need for additional postoperative analgesia among study participants (children 3-14 years of age, ASA I or II). Between groups, no difference was seen in duration of anesthesia and surgery, blood pressure measurements as well as extubation time. Without prolonging the extubation time, dexmedetomidine 1 mcg kg-1 was shown to attenuate the incidence and severity of emergence delirium after tonsillectomy with propofol anesthesia.
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