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Dexmedetomidine facilitates extubation in children who require intubation and respiratory support after airway foreign body retrieval: A case–cohort analysis of 57 cases

Journal of Anesthesia Jun 17, 2018

Zhang X, et al. - In this retrospective case–cohort comparison study, researchers investigated if dexmedetomidine had sedative weaning advantage for extubation after airway foreign body (FB) removal in children. They examined 57 critical children who required mechanical ventilation after rigid bronchoscopy was performed. Following tracheal intubation, two groups were formed: group D (received dexmedetomidine 1 μg/kg over 10 min, followed by an infusion of 0.8 μg/kg/h), and group RP (received remifentanil–propofol 6–10 μg/kg/h and 1–3 mg/kg/h, respectively). They found that dexmedetomidine vs remifentanil–propofol provided high success rate for weaning strategy, in mechanical ventilation of pediatric patients following rigid bronchoscopy.
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