Tan QQ, et al. - Researchers assessed comparative studies comparing the refractive errors in children, birthweights ≤ 1500 grams and gestational ages ≤ 30 weeks, and treatments for Type I retinopathy of prematurity (ROP) with intravitreal bevacizumab (IVB) vs laser photocoagulation in order to ascertain development of refractive error in preterm children with severe ROP managed with anti-VEGF agents and laser photocoagulation. In this study, they included two randomized controlled trials and 5 non-randomized studies, that comprised a total of 272 eyes treated by IVB and 247 eyes treated by laser. Findings revealed an association of treatment with IVB with less myopia and astigmatism than laser treatment for infants with severe ROP. In view of the complexity of ROP and the variability of dosing, they suggest performing close monitoring of refractive error outcomes in children treated with IVB.