Mimura K, et al. - The authors attempted to contemplate the development of neovascular age-related macular degeneration (nAMD) in the fellow eye in patients with unilateral nAMD treated by a treat-and-extend (TAE) regimen with intravitreal aflibercept injections. A substantially more frequent development of nAMD in the fellow eye was revealed in patients with retinal angiomatous proliferation (RAP) compared to other subtypes. Nevertheless, they illustrated considerably less recurrence during the TAE regimen with intravitreal aflibercept injections. Monitoring of the development of nAMD was recommended in the fellow eye in RAP when the injection interval was extended.