van der Lely AJ, et al. - Researchers established and validated a tool to measure disease activity in acromegaly to support decision-making in clinical practice. In context of the findings, the validation study underlined insulin-like growth factor I (IGF-I) and tumor status for routine clinical decision-making, whereas patient-oriented outcome measures received less medical attention. They demonstrated that an Acromegaly Disease Activity Tool (ACRODAT) is in establishment that might assist clinicians towards a more holistic approach to patient management in acromegaly.