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Development of a simple score based on HBeAg and ALT for selecting patients for HBV treatment in Africa

Journal of Hepatology Jul 04, 2018

Shimakawa Y, et al. - A simple score to easily identify patients in need of hepatitis B virus (HBV) treatment in Africa was developed and validated in this analysis. For this investigation, treatment eligibility was used determined by the European Association for the Study of the Liver based on alanine aminotransferase (ALT), liver histology and/or Fibroscan and HBV DNA. Researchers derived a score indicating treatment eligibility by a stepwise logistic regression in The Gambia. The data presented in this work showed a simple score based on HBV e antigen (HBeAg) and ALT had a high diagnostic accuracy for the selection of subjects for HBV treatment and this score could be helpful in African settings.

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