Wong MCS, Rerknimitr R, Goh KL, et al. - A scoring system to identify people at risk for advanced proximal neoplasia (APN) was developed and validated by researchers in this analysis. Data were obtained from 7,954 asymptomatic individuals, aged 50 to 75 years, who received screening colonoscopy examinations at 14 sites in Asia. Five thousand three hundred three individuals were randomly assigned to the derivation cohort and the remaining 2,651 to the validation cohort. Data reported that 79.5% of patients were classified as average risk and 20.5% were classified as high risk in the validation cohort. It was noted that APN prevalence in the average-risk group was 1.9% and in the high-risk group was 9.4%. The score comprised age, smoking habits, colorectal cancer family history and the presence of neoplasia in the distal colorectum. Screening candidates with a score of 4 points or higher who undergo flexible sigmoidoscopy screening will undergo colonoscopy evaluation.