Developing sarcopenia predicts long-term mortality after elective endovascular aortic aneurysm repair
Journal of Vascular Surgery Sep 02, 2019
Lindström I, et al. - Since preoperatively identified sarcopenia as reflected by psoas muscle area (PMA) is correlated with postoperative mortality after repair of abdominal aortic aneurysm (AAA), researchers ascertained if changes in PMA and lean PMA (LPMA) after endovascular aortic repair (EVAR) are related to postoperative survival. PMA and LPMA were evaluated retrospectively from preoperative and 1- and 3-year follow-up CT studies in 122 AAA patients (median age was 77.8 years) treated between 2008 and 2016. During the first year after EVAR, the most significant loss of skeletal muscle occurs. Relative change in PMA during follow-up (ΔPMA/baseline CT muscle parameter) was independently linked to mortality in multivariable analysis. Findings revealed that there was a 21% reduction in the probability of death during follow-up for every 10% unit increase in ΔPMA/baseline CT muscle parameter bilaterally. In patients treated with EVAR, early detection (from CT studies) and sarcopenia prevention may potentially improve survival.
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