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Determinants of trabecular bone score and prevalent vertebral fractures in women with fragility fractures: A cross-sectional sub-study of NoFRACT

Osteoporosis International Nov 29, 2019

Borgen TT, Bjørnerem A, Solberg LB, et al. - In this cross-sectional sub-study of the Norwegian Capture the Fracture Initiative of 496 women aged ≥ 50 years with fragility fractures, researchers investigated the determinants of and the relationships between trabecular bone score (TBS) and SQ1–SQ3 fractures. In multiple variable analyses, higher age, parental hip fracture, and daily alcohol consumption were correlated with lower TBS. Higher BMD of the femoral neck and lumbar spine were related to TBS. In multivariable logistic regression analyses, age and former fragility fractures were positively related to SQ1–SQ3 fractures, while lumbar spine BMD was negatively correlated with SQ1–SQ3 fractures. No relationship between TBS and SQ1–SQ3 fractures was obtained. Thus, since TBS and SQ1–SQ3 fractures were not related, they could act as independent risk factors, warranting the use of both in postfracture risk evaluation.
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