Coles N, Patel BP, Birken C, et al. - Researchers conducted this prospective cohort to assess the effect of in utero exposure to gestational diabetes mellitus (GDM) and maternal weight status on insulin resistance (HOMA‐IR) in the offspring longitudinally from 1 to 3 years of age and to compare BMI and HOMA‐IR in GDM and non‐GDM exposed offspring at 1 and 3 years of age. The sample consisted of children born to mothers with and without GDM who underwent metabolic characterization between birth and 3 years of age. Overall, weight gain in the first 3 years of life was positively correlated with HOMA‐IR, whereas insulin sensitivity of mothers with GDM negatively predicted HOMA‐IR in the offspring. The results suggest the need to target early-life weight trajectories, as well as maternal factors during gestation to improve the offspring's metabolic outcomes, particularly those exposed to GDM.