Tirelli F, Xiao R, Brandon TG, et al. - In this retrospective cohort study, experts aspired to explore whether standardized point-of-care outcome monitoring and clinical decision support (CDS), as compared to standard care, improves disease activity and patient-reported pain in children with enthesitis-related arthritis (ERA). They used multivariable mixed-effects models for repeated measures to ascertain if implementation phase or other disease characteristics were correlated with change over time in disease activity, as measured by the clinical juvenile arthritis disease activity score, and pain. The sample consisted of 152 ERA patients (41% incident cases) with a median age of 14.9 years. In this single center study, there was no major impact of point-of-care outcome monitoring or CDS interventions on disease activity or pain over time in children with ERA. In addition to spondyloarthritis-specific disease activity metrics, future efforts to improve disease outcomes using standardized outcome monitoring and CDS will need to consider the significance of addressing pain as a target.