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Detection of urinary Chlamydia trachomatis, Mycoplasma genitalium and human papilloma virus in the first trimester of pregnancy by PCR method

Annals of Clinical Microbiology and Antimicrobials Jun 08, 2018

Rahimkhani M, et al. - Given that different bacterial (Mycoplasma genitalium and Chlamydia trachomatis as the leading bacterial factor) and viral [human papilloma virus (HPV) as the leading viral factor] infection may cause miscarriage and preterm delivery, researchers analyzed first void urine samples collected from 119 pregnant women. Findings suggested no significant association between urinary isolation of C. trachomatis and miscarriage and no significant association between urinary isolation of M. genitalium and miscarriage. Since all urine samples were PCR-negative, comparison was not possible regarding HPV. Findings suggest that in pregnant women, first void urine samples could be an appropriate sample for detection of C. trachomatis and M. genitalium. However, for HPV isolation, it is not a good method, therefore, they recommend using vaginal or cervical discharge specimens instead for detection of HPV.
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