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Detection of occult neoplastic infiltration in the corpus callosum and prediction of overall survival in patients with glioblastoma using diffusion tensor imaging

European Journal of Radiology Feb 22, 2019

Mohan S, et al. - In this retrospective study, researchers ascertained if diffusion tensor imaging (DTI) can quantify occult tumor infiltration in the corpus callosum (CC) and predict the overall survival in patients with glioblastoma (GBM). For this investigation, they assessed 48 patients with pathologically proven GBM and 17 healthy volunteers. All patients had DTI at 3T MRI scanner. Findings suggested that fractional anisotropy (FA) values from the CC could quantify occult tumor infiltration and serve as a sensitive prognostic marker for overall survival prediction in GBM patients.

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