Azizi S, et al. - Researchers here sought to establish the pick-up rates of dysplastic or cancerous lesions using white light endoscopy (WLE) and random/targeted biopsies, or chromoendoscopy (CE), in patients with ulcerative colitis (UC) without primary sclerosing (PSC) or Crohn's disease (CD). Among UC patients without PSC, endoscopic examination identified dysplastic or cancerous lesions in 5–7% of cases. WLE and random biopsies could pick-up a similar number of lesions to targeted biopsies, however, the number of biopsies might need to be greater to achieve this equivalence. CE demonstrated a slightly higher pick-up rate.