Detailed optical coherence tomography angiographic short‐term response of type 3 neovascularization to combined treatment with photodynamic therapy and intravitreal bevacizumab
Acta Ophthalmologica Mar 20, 2021
Smid LM, Vermeer KA, Wong KT, et al. - In this prospective observational cohort study, researchers explored the short‐term vascular and structural changes of type 3 neovascularization using optical coherence tomography angiography (OCT‐A) when treated with a combination of photodynamic therapy (PDT) and intravitreal bevacizumab (IVB) and assessed the course of different sequences of the combined therapies. Thirty eyes of 29 treatment‐naïve patients with a type 3 neovascularization were involved and all were treated with PDT and IVB 2 weeks apart, starting either with PDT (PDT‐first group) or IVB (IVB‐first group). Based on vascular and structural features, combined treatment of PDT and IVB is effective in the short‐term for type 3 neovascularization. PDT was more effective than IVB as an initial treatment.
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