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Derivation and external validation of a scoring system for predicting fracture risk after ischemic stroke in a Canadian cohort

JAMA Neurology May 18, 2019

Smith EE, et al. - For determination of a risk score that predicts the probability of fracture in patients who had an ischemic stroke in the past year, included a total of 20,435 patients admitted for ischemic stroke who were analyzed to create the Fracture Risk after Ischemic Stroke (FRAC-Stroke) score. Of these patients, 3.6% had a nontraumatic fracture within 1 year after stroke. A combination of 7 features, including global stroke disability, was used for the FRAC-Stroke score, which could predict fracture risk with good discrimination. In selecting the patients for interventions, like bone densitometry screening or, for very high-risk patients, empirical bisphosphonate therapy, this information might prove useful.

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