Deka P, Almenar L, Pathak D, et al. - Findings demonstrate that depression can influence physical and psychological readiness to perform physical activity (PA) in patients with heart failure (HF), and thus, screening for depression is recommended throughout the trajectory of the disease in HF patients.

• This cross-sectional study included 163 New York Heart Association Class I and II HF patients.

• The mediating impact of depression on PA readiness (physical limitation and psychological readiness) and self-reported PA was investigated.

• Depression fully mediated the impact of physical limitation as well as partially mediated the impact of self-efficacy on PA.

• There was an independent and significant impact of both intrinsic and extrinsic motivation for PA on PA, not mediated by depression.