Delayed systolic blood pressure recovery following exercise as a mechanism of masked uncontrolled hypertension in chronic kidney disease
Nephrology Dialysis Transplantation Oct 06, 2017
Agarwal R, et al. - This study investigated if hemodynamic reactivity to exercise is increased in patients with masked uncontrolled hypertension (MUCH) and if these patients have delayed hemodynamic recovery following exercise. As heart rate recovery among groups was not impaired, researchers speculated that the parasympathetic pathway appears intact among treated hypertensives with chronic kidney disease (CKD). However, after exercise termination, no cessation of ongoing vasoconstriction was noted due to failure to withdraw sympathetic tone and, rather systolic blood pressure (BP) recovery was found to be delayed offering a biological basis for MUCH. Delayed recovery from exercise-induced hypertension in those with poorly controlled BP provides potentially a new target to assure round-the-clock BP control.
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