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Delayed cerebral ischaemia in patients with aneurysmal subarachnoid haemorrhage: Functional outcome and long-term mortality

Acta Anaesthesiologica Scandinavica Jun 14, 2019

Olsen MH, et al. - Among patients with aneurysmal subarachnoid haemorrhage (aSAH), researchers examined the link between delayed cerebral ischaemia (DCI), functional outcome and 4-year mortality. DCI was defined as either a reduction in consciousness or focal neurological deficits lasting ≥1 hour without any other detectable cause. Three groups of patients were defined: those with DCI; those without DCI; and those who were unassessable for DCI. The best functional outcome (modified Rankin Scale) was found in patients without DCI vs those with DCI and those who were unassessable; furthermore, worse outcomes were seen in the latter as compared with patients with DCI. Significantly higher mortality was observed in patients diagnosed with DCI vs those without DCI, even ignoring the first 14 days post-admission. Overall, findings are suggestive of a possible association of DCI with both short- and long-term morbidity and mortality in patients with aSAH.
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