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Degeneration of the inferior cerebellar peduncle after middle cerebral artery stroke: Another perspective on crossed cerebellar diaschisis

Stroke Aug 31, 2019

Kim JS, Kim SH, Lim SH, et al. - Via retrospectively involving 23 patients admitted to the inpatient rehabilitation facility and 23 age-matched healthy controls, researchers ascertained if changes in the spinocerebellar pathway occur after middle cerebral artery stroke. As the final route of the dorsal spinocerebellar pathway, the fractional anisotropy (FA) values of the corticospinal tract and the inferior cerebellar peduncle (ICP) were compared between groups. In the patient group, the FAs of the corticospinal tract and ICP were lower than in the control group. According to the multivariate regression models, the FA laterality index of the ICP at the pontomedullary junction was independently linked to the functional ambulation category. In the subacute and early chronic phase of middle cerebral artery stroke, ICP degeneration occurs. The ICP's lower FA laterality index indicated poorer ambulatory and lower limb function.
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