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Definitions, prevalence, clinical implications and treatment of T‐shaped uterus: Systematic review

Ultrasound in Obstetrics & Gynecology Sep 16, 2020

Neto MAC, Ludwin A, Petraglia F, et al. - Via performing a systematic review, researchers sought to summarize the current evidence concerning definitions, diagnosis, prevalence, clinical implications and impact of surgical treatment for T‐shaped uterus not related to Diethystilbestrol (DES) exposure. In addition, they highlight what needs to be better clarified regarding T‐shaped uterus. Searching PubMed, Scopus and EMBASE on Mar‐2020, they identified 2,504 records and included 20 studies in the systematic review. Only poor‐quality studies were there (observational and quasi‐experimental with uncontrolled before‐after design) Most of these studies (11/16 studies) employed three‐dimensional US (3D‐US) for diagnosing T‐shaped uterus. The criteria from European Society of Human Reproduction and Embryology and the European Society for Gynecological Endoscopy (ESHRE/ESGE) 2013 (narrow uterine cavity due to thickened lateral walls with a correlation 2/3 uterine corpus and 1/3 cervix), which is subjective, were the most cited criteria (4/16 studies). The included studies had T‐shaped uterus prevalence ranging from 0.2%‐10%. T‐shaped uterus was reported to be related with worse reproductive outcomes due to infertility (9 studies), miscarriage (7 studies), preterm delivery (2 studies), ectopic pregnancy (1 study) and repeated implantation failure (7 studies). As the evidence gained were of poor quality, no robust information concerning diagnosis, prevalence, and clinical relevance on reproductive outcomes in women with T‐shaped uterus could be gained. They suggest considering expectant management as the most appropriate choice for daily practice until randomized controlled trials shows otherwise.

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