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Definition of a clinical strategy to enhance the efficacy, efficiency and safety of egg donation cycles with imported vitrified oocytes

Human Reproduction Apr 06, 2020

Rienzi L, Cimadomo D, Maggiulli R, et al. - Researchers sought to determine the most suitable clinical strategy in egg donation IVF cycles conducted with imported donated vitrified oocytes. In this longitudinal cohort study, 273 couples treated (mean maternal age: 42.5 ± 3.5 years, range: 31–50 years; mean donor age: 25.7 ± 4.2, 20–35 years) with oocytes purchased from three different Spanish egg banks were assessed from October 2015 and December 2018 at two private IVF centers. This study was undertaken to devise a workflow to maximize IVF efficacy, efficiency, and safety, during egg donation cycles with imported vitrified oocytes. Outcomes revealed a high cumulative live birth delivery rate per cycle, as well as the confident adoption of a single blastocyst transfer strategy to minimize the risk of multiple pregnancies, in correlation with the importation, and allocation, of at least eight vitrified eggs per couple during an egg donation cycle.

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