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Defining a cohort of oligometastatic nasopharyngeal carcinoma patients with improved clinical outcomes

Head & Neck Feb 05, 2020

Chee J, Liu X, Eu D, et al. - Researchers conducted this retrospective review to contrast the clinical results of oligometastatic vs widely metastatic nasopharyngeal carcinoma (NPC) patients. The sample consisted of 157 individuals with metastatic NPC at a tertiary hospital. In order to compare the overall and progression-free survival (OS and PFS) of these two cohorts of NPC patients, multivariate analysis was carried out. Compared with patients with widespread metastasis, those with oligometastatic NPC (single organ, less than six discrete metastatic lesions) had a better median OS. Likewise, oligometastatic NPC's median PFS was better than polymetastatic NPC's. Findings suggested that single organ disease with less than six discrete lesions was a good indicator of limited metastatic load in NPC, and was linked to improved survival.
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