Deep sequencing shows that oocytes are not prone to accumulate mtDNA heteroplasmic mutations during ovarian ageing
Human Reproduction Sep 01, 2017
Boucret L, et al. – The purpose of this study is to determine whether ovarian ageing increase the number of heteroplasmic mitochondrial DNA (mtDNA) point mutations in oocytes. These outcomes propose that oocytes are not subject to the accumulation of mtDNA point mutations amid ovarian ageing.
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