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Deep neuromuscular blockade during spinal surgery reduces intra-operative blood loss: A randomised clinical trial

European Journal of Anaesthesiology Feb 13, 2020

Kang WS, Oh CS, Rhee KY, et al. - In this randomised, single blinded trial, researchers tested the assumption that deep neuromuscular blockade would be correlated with less surgical bleeding during spinal surgery in the prone position. Participants in the study were 88 patients in two groups. Study participants were randomly assigned to moderate neuromuscular blockade or deep neuromuscular blockade. In patients undergoing spinal surgery, deep neuromuscular blockade decreased intra-operative surgical bleeding. This can be associated with increased relaxation in the back muscles and lower intra-operative peak inspiratory pressure relative to moderate neuromuscular blockade.
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