Kristensen PK, et al. - Recent time trends in the utilization of narrow- and broad-spectrum antibiotics were determined in addition to assessing variation in antibiotic use by sex, age, and municipality of residence. Researchers analyzed complete individual-level data on all redeemed out-of hospital prescriptions for antibiotics in the entire adult population of Central Denmark (1.3 million inhabitants) for the period 2006–2015. Outcomes revealed decerease in antibiotic use by almost 20% in Central Denmark after 2011. This is possibly related to a nationwide antibiotic stewardship program in Denmark. However, there remained a substantial geographical variation in antibiotic prescription. Among adults of older age, an increase in the use of broad-spectrum antibiotics was observed. They emphasize continuously focussing on avoiding unnecessary use of broad-spectrum antibiotics.