Eikmeier D, Talley P, Bowen A, et al. - Given the worldwide reporting of Shigellosis outbreaks caused by Shigella with decreased susceptibility to azithromycin (DSA-Shigella) among men who have sex with men (MSM), researchers sought to report sexual health indicators and antimicrobial drug resistance for shigellosis cases in Minnesota, USA. They performed analysis of a sample of isolates received during 2012–2015 as well as cross-referenced cases with the Minnesota Department of Health Sexually Transmitted Disease Database to determine patients’ HIV status and recent chlamydia, gonorrhea, and syphilis infections. Amongst 691 Shigella isolates, 46 (7%) were identified as DSA-Shigella. Among DSA-Shigella patients, 91% were men, of whom 60% were living with HIV. Greater odds of living with HIV, identifying as MSM, or having a recent diagnosis of a sexually transmitted disease were observed among men with DSA-Shigella infection. They observed an association of DSA-Shigella with MSM, HIV infection, and recent sexually transmitted disease. Findings suggest the necessity for interventions targeting communities at high risk in order to reduce the spread of DSA-Shigella.