Chen N, Shi J, Li Y, et al. - As previous studies in major depressive disorder (MDD) mainly focused on detecting non-overlapping sub-networks/communities, neglecting the possibility that one brain region may belong to multiple sub-networks/communities, researchers here used tensor decomposition method to determine overlapping communities and assess the dynamism of overlapping sub-networks. They enrolled 58 patients with MDD and 63 age- and gender-matched healthy controls (HC). The statistical significance of the differences in dynamism of MDD and HC groups was determined by calculating strength vectors of communities and performing two-sample t-test. Communities detected in two groups were noted to be pairwise region-matching but overlapped brain regions were identified to be almost totally different. Significantly reduced dynamism was noted in five sub-networks, in MDD patients vs HCs, which could be functionally mapped to Visual Network (VN), Default Mode Network (DMN), Cognitive Control Network (CCN), Bilateral Limbic Network (BLN) and Auditory Network (AN). Per results, MDD seems to have only a marginal effect on the holistic identification of communities and the changes of overlapped brain regions in MDD patients might be put down to the alteration of hubs. Further statistical analysis on nine sub-networks indicated reduced dynamism of five sub-networks in MDD patients, which could allow a better understanding of the mechanism in MDD.