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Decreased anterior cingulate activation in a motor task in youths with bipolar disorder

Journal of Child Psychology and Psychiatry Feb 25, 2018

King JB, et al. - During the completion of a simple motor task, a comparison of brain activation patterns in motor networks between euthymic youths with Bipolar disorder (BP) and healthy controls (HC) was performed. In the anterior cingulate cortex (ACC), youths with BP compared to HC showed significantly decreased activation. Furthermore, the BP group indicated a negative correlation between ACC activation and Child Behavior Checklist mood dysregulation profile scores. Findings thereby suggested a potential common mechanism of impaired ACC modulation between emotion dysregulation and motor processing in youths with BP.
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