Zidane M, et al. - Researchers sought to determine the most time-effective sequence of systemic induction treatments for moderate to severe plaque psoriasis. Using a decision-analytic model set in the German healthcare system, this time-effectiveness analysis in a simulated population of adults with plaque psoriasis indicated that the most time-effective treatment was treatment sequence starting with ixekizumab (1.4 weeks for a minimally important difference in Dermatology Life Quality Index score) and that time-efficacy was higher for sequences starting with a biological agent than the most frequently used treatment sequences in Germany. The results were robust to deterministic sensitivity analyses. As per these results, they suggest that a possible consideration could be given to the time until patients experience a minimally important difference in their quality of life as an additional outcome measure when allocating monetary resources.