Chaiyakit P, Meknavin S, Hongku N, et al. - Researchers aimed at describing the outcomes of patients presenting with acute hematogenous periprosthetic joint infection (PJI) after total knee arthroplasty (TKA) who received debridement, antibiotics, and implant retention (DAIR) combined with direct intra-articular antibiotic infusion. This method was used in semi-urgent treatment of 15 knees in 12 patients. The mean follow-up time period of 93.3 (minimum: 56) months was recorded, and the longest follow-up time was 11 years. Outcomes suggest that for acute hematogenous PJI after TKA, DAIR combined with direct intra-articular antibiotic infusion is an effective therapeutic option.