Vanezis AP, et al. - Given repeated remote ischaemic conditioning (rIC) post myocardial infarction may provide additional benefits, researchers evaluated the role of daily rIC in enhancing left ventricular ejection fraction (LVEF) recovery in patients with impaired LVEF (<45%) after ST segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (P-PCI). From day 3 post P-PCI, either 4 weeks of daily rIC or sham conditioning using the autoRIC Device (CellAegis) was provided to patients recruited from four UK hospitals. The primary endpoint was the improvement in LVEF over 4 months assessed by cardiac MRI (CMR). Relative to a matched control group, no improvement was seen in CMR-assessed LVEF over 4 months in patients who received daily rIC starting on day 3 and continued for 4 weeks following successful P-PCI for STEMI.