Chalmers JR, Haines RH, Bradshaw LE, et al. - This study was attempted to investigate whether daily use of emollient in the first year could prevent eczema in high-risk children. Researchers conducted a multicentre, pragmatic, parallel-group, randomized controlled trial in 12 hospitals and four primary care sites across the UK. Via antenatal or postnatal services, families were addressed for recruitment of term infants (at least 37 weeks' gestation) at high risk of developing eczema (ie, at least one first-degree relative with parent-reported eczema, allergic rhinitis, or asthma, diagnosed by a doctor). Between Nov 19, 2014, and Nov 18, 2016, they randomized 1,394 newborns to study groups (693 were assigned to the emollient group and 701 to the control group). No evidence that daily emollient during the first year of life prevents eczema was found in high-risk children and some data to intimate an increased risk of skin infections. The outcomes of this research indicated that families with eczema, asthma, or allergic rhinitis should not use daily emollients to try and prevent eczema in their newborn.