Ruiz J, et al. – Authors undertake this work to assess the effectiveness of chlorhexidine gluconate (CHG)–impregnated wipes in the daily bathing of patients in an intensive care unit (ICU) to prevent cross–transmission and colonization by multidrug–resistant organisms (MDROs). As per findings, the use of CHG–impregnated wipes reduces cross–transmission and colonization by MDROs in the ICUs in an endemic situation because of multidrug–resistant Enterobacteriaceae.