Kulthanan K, et al. - Cyclosporine A (CsA) was appraised as a treatment option for chronic spontaneous urticaria (CSU) in a meta-analysis and review. Data suggested the efficacy of CsA at low to moderate doses. Adverse events seemed to be dependent on the dose and were reported in more than half the patients treated with moderate doses of CsA. Notably, 1 to 5 mg/kg/d was recommended as the potentially appropriate dosage of CsA for CSU, and 3 mg/kg/d was a reasonable starting dose for most patients.