Zazzaron M - The author conducted this descriptive, retrospective, observational, monocentric study to provide a specific treatment approach for clinically different lips based on their clinical experience. The study sample consisted of patients attending the Zazzaron Aesthetic Medicine ambu-latory (Treviso, Italy) for a lip improvement procedure with HA-based products between 2016 and 2017. The investigator used a Medicis Lip Fullness Scale (MLFS) to measure the fullness of the lip at first visit (T0) and at 2 weeks (T1). A weak positive relationship has been observed between MLFS responses and subject's GAIS at T1 in all groups. This customized treatment approach, consisting of selecting the right gel technology injected with the right technique in minimum quantities, provides a harmonic outcome that prevents aberrations and standardizations.