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Curative effect of second curettage for treatment of Gestational trophoblastic disease - Results of the Belgian registry for Gestational trophoblastic disease

European Journal of Obstetrics & Gynecology and Reproductive Biology Dec 15, 2020

Vandewal A, Delbecque K, Van Rompuy AS, et al. - Using data of the Belgian register for gestational trophoblastic disease (GTD), researchers conducted this prospective observational study with the aim to assess the curative effect of a second curettage in patients with persistent hCG serum levels after first curettage for a GTD. This work is identified to be the first study performed by the Belgian Register for Trophoblastic Diseases. The aim of this registry is to enhance patient care and facilitate research on the subject of GTD. A second curettage was performed on 37 patients of the study population (12%). Per findings, a second curettage can benefit patients with postmole gestational trophoblastic neoplasia to avoid chemotherapy. Higher success rates are noted when hCG level is lower than 5,000 IU/L and these are even more if hCG is below 1,000 IU/L

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