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CT staging to triage selection of patients with poor-prognosis rectal cancer for neoadjuvant treatment

American Journal of Roentgenology Apr 25, 2019

Ortega CD, et al. - In a scenario of limited availability of MRI, researchers assessed CT as a screening tool to determine the high risk of local rectal tumor recurrence. The study involved 180 consecutively registered patients with rectal adenocarcinoma and no previous treatment with CT and MRI stages within 30 days of each other. Of the 180 patients, 128 met high-risk local recurrence MRI criteria. Data reported that CT sensitivity was 84.4% and specificity was 78.8%. Findings revealed that the positive predictive value of any high-risk CT feature was 90.7%. Without baseline MRI, tumors at high risk of local recurrence can be identified with CT. According to this retrospective analysis, using CT rather than MRI could significantly reduce baseline staging costs and shorten the time for neoadjuvant therapy initiation.
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