Cheng J, et al. - In this retrospective study, researchers studied 3-year progression-free survival (PFS) in patients with stage T4a gastric cancer with extramural vessel invasion (EMVI) spotted with contrast-enhanced (CE) MDCT and assessed if CT of EMVI could enhance clinical nodal (N) staging. Participants in the study were 143 patients with T4a gastric cancer. Data revealed that the EMVI frequency at CT was 55.9%. For the EMVI positive–N positive group, the 3-year PFS rates were 25.0%, in the EMVI positive–N negative group it was 53.1%, in the EMVI negative–N positive group it was 75.6% and in the EMVI negative–N negative group it was 64.7%. In patients with T4a gastric cancer, EMVI spotted at CT combined with N status detected with CE-MDCT could be used as a valuable preoperative prognostic factor. EMVI positive–N positive status was assessed to be an independent predictor of reduced 3-year PFS.