Le Joncour A, et al. - Researchers assessed the role of neutrophil extracellular traps (NETs) and markers of NETs in Behçet’s disease (BD), a chronic systemic vasculitis. They obtained blood samples from healthy donors and from patients with BD, using the International Study Group Criteria for Behçet's disease. From both groups, serum or purified neutrophils were extracted in which NET components, including cell-free DNA and neutrophil enzymes myeloperoxidase, were evaluated. Patients with BD exhibited elevated levels of NETs and markers of NETS. Also, NETs and markers of NETS contributed to the procoagulant state in these patients. In order to attenuate or prevent BD-related thrombotic risk, a potential therapeutic target could be NETs.