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Cranial and large vessel activity on positron emission tomography scan at diagnosis and 6 months in giant cell arteritis

International Journal of Rheumatic Diseases Mar 07, 2020

Sammel AM, Hsiao E, Schembri G, et al. - In order to ascertain the change and significance of vascular activity at diagnosis and 6 months, researchers included 21 giant cell arteritis (GCA) individuals and 15 underwent the serial scan. This study included newly diagnosed GCA individuals who underwent time-of-flight fluorine-18-fluoro-2-deoxyglucose PET/CT from vertex to diaphragm within 72 hours of commencing corticosteroids and were followed for 12 months. They carried out a 6 months scan in individuals with inflammatory features on biopsy or CT aortitis. The outcomes of this study indicated that vascular activity decreased in cranial and large arteries between diagnosis and 6 months. Persistent activity did not predict subsequent relapse.
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