COVID-19 as an independent risk factor for subclinical placental dysfunction
European Journal of Obstetrics & Gynecology and Reproductive Biology Feb 04, 2021
Jaiswal N, Puri M, Agarwal K, et al. - Via performing a prospective analytical study, researchers sought to determine the histopathological alterations in the placenta of SARS-CoV-2 positive pregnancies with either no symptoms or mild coronavirus disease (COVID)-19 related symptoms. In addition, they examined its correlation with neonatal outcomes. Cases were 27 asymptomatic or mildly symptomatic SARS-CoV-2 positive pregnant women with a singleton pregnancy and controls were an equal number of SARS-CoV-2 negative singleton pregnancies matched for maternal and gestational age during the same period. In line with findings from other studies, this study yielded evidence of placental injury at a microscopic level in asymptomatic or mildly symptomatic SARS-CoV-2 positive pregnant women, with otherwise uncomplicated pregnancies. Apparently, this placental injury does not result in poor pregnancy outcomes.
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