Chidambaran V, et al. - Researchers implemented this prospective cohort study to model cost-effectiveness of adding acetaminophen or acetaminophen + ketorolac to opioids for postoperative outcomes in children having scoliosis surgery. Findings demonstrated that compared with opioids-alone postoperative analgesia strategy, intravenous acetaminophen with or without ketorolac attenuated opioid consumption, opioid-related adverse effects, length of stay, and thereby cost of care after idiopathic scoliosis in adolescents.