Taxbro K, et al. - Researchers used various clinically important dimensions from a health care perspective, to determine the cost associated with peripherally inserted central catheters (PICCs) and totally implanted chest ports (PORTs), which are commonly used for the delivery of chemotherapy in cancer patients, by performing a health economic assessment in this randomised controlled trial with 399 patients with cancer. For PICC and for PORT, the prize per inserted device was estimated to be 824.58 EUR and 662.34 EUR, respectively, merging the costs of all categories. For PICC and for PORT, the price was estimated to be 6.58 EUR/day and 3.01 EUR/day, respectively, when adjusting for total catheter dwell time. Overall, from a healthcare perspective, a higher cost was incurred by the use of a PICC vs a PORT in cancer patients. The main driver of the difference was the cost associated with the management of adverse events. The relevance of these results is for anaesthetists, oncologists and vascular access clinicians, and taking these data into account when selecting vascular access device before chemotherapy was recommended.