Munguía-Calzada P, et al. - Researchers examined how focal adhesion kinase (FAK) and cortactin expression are correlated with the clinicopathologic features and the impact on the prognosis of cutaneous squamous cell carcinoma (cSCC) patients. Using immunohistochemistry on paraffin-embedded tissue samples from 100 patients with cSCC, and correlated with the clinical data, they analyzed FAK and cortactin expression. Findings revealed the independent predictive value of FAK overexpression for nodal metastasis. This may help in risk stratification and management of patients with cSCC.