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Correlation of exhaled nasal nitric oxide with sinus computed tomography and sinonasal outcome test scores: A cross-sectional pilot study

American Journal of Rhinology & Allergy Sep 28, 2018

Oliver JD, et al. - Researchers evaluated how passive (baseline) and dynamic (humming) nasal nitric oxide (nNO) impact computed tomography (CT) findings of sinus inflammation and sinonasal symptoms measured by the modified Sinonasal Outcome Test (26 items) (SNOT-26). Patients had baseline and humming nNO levels assessed with a chemiluminescence NO analyzer, and each patient underwent CT imaging and completed the SNOT-26 survey. Results demonstrated that baseline passive nNO could be a useful and inexpensive point-of-care screening test for sinonasal opacification. Nonetheless, there was an association of baseline nNO levels with Lund–Mackay and SNOT-26 scores; humming nNO levels did not show a comparable correlation.

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