Correlation between the number of ghrelin-secreting cells in the gastric fundus and excess weight loss after sleeve gastrectomy
Obesity Surgery Sep 07, 2018
Itlaybah A, et al. - Via examining 39 patients (mean age of 33.7 years), researchers investigated the correlation between the number of ghrelin-secreting cells in the gastric fundus and excess weight loss (EWL) at 12 months after laparoscopic sleeve gastrectomy (LSG). They measured the surface area of the gastric fundus postoperatively in square centimeter and the number of ghrelin-secreting cells per square centimeter via a histopathologic examination of the gastric fundus. The two measures were then multiplied to calculate the total number of ghrelin-secreting cells in the fundus. Findings revealed a weak correlation between the total number of ghrelin-producing cells in the gastric fundus and plasma ghrelin levels with EWL after LSG.
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