Li X, Zhang T, Li S, et al. - Given that patients with polycystic ovary syndrome (PCOS) show abnormal patterns of steroid hormones, researchers conducted this observational double-centre study to determine if there is an association between glucose metabolism and serum steroid hormones in PCOS. Study participants included 914 patients [median age was 26 years (interquartile range: 21-30)] with PCOS who visited Ruijin Hospital and Renji Hospital in Shanghai from January 2006 to October 2016. Only aldosterone, androstenedione and estrone (in quartiles) were associated with the risk of abnormal glucose metabolism after adjusting for age, BMI and fasting insulin levels in the logistic regression model. The data presented in this work showed a high prevalence of prediabetes and T2DM in patients with PCOS. Additionally, after adjustment for confounding factors, there were positive associations of serum aldosterone, androstenedione, and estrone with the risk of abnormal glucose metabolism.