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Correlation between apparent diffusion coefficient values of the renal parenchyma and estimated glomerular filtration rates on 3-T diffusion-weighted echo-planar magnetic resonance imaging

Journal of Computer Assisted Tomography Sep 26, 2019

Thiravit S, et al. - Data on 216 patients investigated by 3-T magnetic resonance imaging for different reasons were retrospectively gathered to assess the association between the apparent diffusion coefficient (ADC) values of renal parenchyma and estimated glomerular filtration rates (eGFR). A notable linear relationship between the ADC values and eGFRs were noted. In patients with an eGFR of less than 60 mL/min per 1.73 m2, the ADC values were significantly lower than those with an eGFR of 60 mL/min per 1.73 m2 or greater. The mean ADC value of individuals with grouped stage 2 disease was significantly greater in comparison with those with grouped stage 3 of chronic kidney disease. Therefore, the ADC value of renal parenchyma could be a promising marker for the ascertainment of patients with normal to a mild decrease in renal function (eGFR ≥60 mL/min per 1.73 m2) than those with a moderate to a severe decline in renal function (eGFR <60 mL/min per 1.73 m2).
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