Smilowitz NR, Galloway AC, Ohman EM, et al. - Given a high mortality related to cardiogenic shock (CS) complicating acute myocardial infarction (MI), researchers ascertained contemporary coronary revascularization as well as circulatory support strategies for MI with CS and multi-vessel coronary artery disease (CAD), by performing a survey among interventional cardiologists and cardiothoracic surgeons. The survey was completed by 143 participants. Single vessel PCI of the infarct related artery (IRA) with staged PCI of non-culprit lesions was stated as the standard approach to coronary revascularization, according to 55.2% of participants. At some centers, standard approaches included single vessel PCI of the IRA only (28.0%), emergency multi-vessel PCI (11.9%), and coronary artery bypass grafting (CABG) (4.9%). Impella (76.9%), intra-aortic balloon pump (IABP) (12.8%), and extra-corporeal membrane oxygenation (ECMO) (7.7%) were reported as the preferred choices after PCI for CS. Preference was given to IABP (34.3%), Impella (32.2%), and ECMO (28%) following CABG. Findings revealed substantial heterogeneity in clinical care in CS. Experts found proof of provider uncertainty as well as clinical equipoise concerning the optimal treatment of patients having MI, multi-vessel CAD, and CS.